Dear All: I'm almost at the end of my second month on Leflunomide. I'm having some side-effects (rectal pain!), painful wrist, increased thirst and urination, occasional headaches and upset stomachs. My GP is aware of these. unfortunately I just finished a two month ciourse of Prednisole as my knees were badly swollen. Now I'm finished these my knees are really swollen again. I've just recently started a new job and I've not broadcast about the RA. I'm trying to appear as normal as possible!!! It is increasingly difficult to walk normally so I won't be able to hide it next week...then the questions start!

I want to take three doses of full strenght Ibuprofen to see if this will decrease the swelling at all. i've not been advised to not take it, but has anyone else done this. So far the Leflunomide has not kicked in. Though I have noticed that the stiffness has not come back...maybe the weather being warmer???

My bloods are all wonky but nothing too serious.

Thanks.
J

Sorry, posted twice!

Hello

Just thought I'd let you know that I take diclofenac regularly (everyday) with leuflunomide. Diclofenac works in the same way as ibuprofen but is stronger. I suggest you ask your GP to prescribe this. Make sure he also prescribes a stomach protector such as omeprazole aswell.

Becky

Hi Jan,

Hopefully the secretary will get back to you with an appointment, it sounds as if your knees maybe need aspirating ,they usually put steroid in when they do this and it's very effective.
You could ring the NRAS helpline for advice on the care (or lack of!) you are getting.
Hope you get some help soon.

Love Doreen xx

PS have you tried ice on your knees? 20 minutes on, 20 minutes off, see if it helps.